Smith reports on cell capture and growth research in Tissue Engineering

In a collaboration between the Cornell Micro/Nanofluidics Lab and the Biological Surface Engineering and Microfluidics Laboratory at Northeastern University, we recently published on “Microfluidic enrichment of mouse epidermal stem cells and validation of stem cell proliferation in vitro,” in the journal Tissue Engineering C with Beili Zhu and Shashi Murthy of Northeastern University and Brian Kirby at Cornell.  We isolate bulge stem cells from mice in under 30 minutes using a microfluidic platform, and show that these cells remain viable and grown in culture.  My CFD simulations, detailed in this paper, led to an eight-fold improvement in sample purity as compared to previous stem cell isolation devices.

The article’s abstract and a downloadable PDF are available on my publications page.