My paper “Enrichment of prostate cancer cells from blood cells with a hybrid dielectrophoresis and immunocapture microfluidic system” was recently published in the journal Biomedical Microdevices. This paper describes my work on characterizing cancer cell enrichment from blood cells using a combination of dielectrophoresis (DEP) and immunocapture techniques. I showed that dielectrophoresis can enhance the capture of prostate cancer cells while reducing the nonspecific adhesion of peripheral blood mononuclear cells to immunocapture surfaces. This work informs the design of future hybrid DEP-immunocapture devices for high-purity rare cell capture.
Huang C, Liu H, Bander NH, Kirby BJ. “Enrichment of prostate cancer cells from blood cells with a hybrid dielectrophoresis and immunocapture microfluidic system,” Biomedical Microdevices, 15(6): 941-8, 2013. DOI